产品名称 MK 0524 sodium salt - Laropiprant
产品货号 Axon 1480 CAS [572874-50-1] MF C21H18ClFNNaO4SMW 457.88 Purity: 99% Optical purity: Optically pure Soluble in water and Ethanol Description Potent and selective prostaglandin D2 (PGD2) receptor 1 (DP1) antagonist; Ki values to be 0.57 nM and 750 nM for DP1 and DP2 receptors respectively References Certificates Categories Extra info K Chang et al. Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans. PNAS 2006, 103(17), 6682-6687.    CF Sturino et al. Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524). J. Med. Chem. 2007, 50(4), 794-806.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology Pain & Inflammation PGD2 (DP1) A14 PGD2 receptor DP1 antagonist Chemical name [(R)-4-(4-chloro-benzyl)-7-fluoro-5-methanesulfonyl-1,2,3,4-tetrahydro-cyclopenta[b]indol-3-yl]-acetate sodium salt Parent CAS No. [571170-77-9] Order Size Unit Price Stock 5 mg €125.00 In Stock
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MK 0524 sodium salt - Laropiprant

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1480

CAS [572874-50-1]

MF C21H18ClFNNaO4S
MW 457.88

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and Ethanol

MK 0524 sodium salt

Description

Potent and selective prostaglandin D2 (PGD2) receptor 1 (DP1) antagonist; Ki values to be 0.57 nM and 750 nM for DP1 and DP2 receptors respectively
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