产品名称

Flumethasone pivalate - Locorten | NSC 107680

产品货号

Axon 2247 CAS [2002-29-1] MF C27H36F2O6MW 494.57 Purity: 99% Soluble in DMSO and Ethanol Description Topical glucocorticoid receptor agonist. Flumethasone pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. References Certificates Categories Extra info M. Baeck et al. Corticosteroid cross-reactivity: clinical and molecular modelling tools. Allergy 2011, 66, 1367–1374. N. Bodor et al. Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach. J. Med. Chem. 1983, 26, 318-328. S. Höller et al. Effect of selected fluorinated drugs in a "ringing" gel on rheological behaviour and skin permeation. Eur. J. Pharm. Biopharm. 2007, 66, 120-126. Flumethasone pivalate (Locorten) and other topical steroids. Med. Lett. Drugs Ther. 1971, 13, 33-35. Certificate of Analysis Material Safety Data Sheet Cardiovascular Miscellaneous Pain & Inflammation NR3C Glucocorticoid (GR) Topical glucocorticoid receptor agonist Chemical name 2-((6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl pivalate Parent CAS No. [2002-29-1] Order Size Unit Price Stock 10 mg €60.00 In Stock

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产品品牌

axonmedchem

产品概述

产品详情

Flumethasone pivalate - Locorten | NSC 107680

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2247

CAS [2002-29-1]

MF C27H36F2O6
MW 494.57

Purity: 99%
Soluble in DMSO and Ethanol

Flumethasone pivalate

Description

Topical glucocorticoid receptor agonist. Flumethasone pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties.

M. Baeck et al. Corticosteroid cross-reactivity: clinical and molecular modelling tools. Allergy 2011, 66, 1367–1374.

N. Bodor et al. Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach. J. Med. Chem. 1983, 26, 318-328.

S. Höller et al. Effect of selected fluorinated drugs in a "ringing" gel on rheological behaviour and skin permeation. Eur. J. Pharm. Biopharm. 2007, 66, 120-126.

Flumethasone pivalate (Locorten) and other topical steroids. Med. Lett. Drugs Ther. 1971, 13, 33-35.

Topical glucocorticoid receptor agonist

Chemical name

2-((6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl pivalate

Parent CAS No.

[2002-29-1]

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