产品名称 | Vildagliptin - NVP-LAF 237 |
产品货号 | Axon 1631 CAS [274901-16-5] MF C17H25N3O2MW 303.40 Purity: 99% Optical purity: Optically pure Soluble in water Description Highly potent, selective and orally bioavailable inhibitor of dipeptidyl peptidase-4 (DPP4), with IC50 to be 2.3 and 2.7 nM for rat and human plasma DPP4 References Certificates Categories Extra info MA Sallas et al. Vildagliptin, a dipetidyl peptidase-IV inhibitor, improves model-assessed β-cell function in patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 2005, 90, 4888–4894. UV Wesley et al. Dipeptidyl peptidase inhibits malignant phenotype of prostate cancer cells by blocking basic fibroblast growth factor signaling pathway. Cancer Res. 2005, 65(4), 1325–34. EB Villhauer et al. 1-(3-hydroxy-1-adamantyl)aminoacetyl-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J. Med. Chem. 2003, 46, 2774-2789. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism DPP4 EC 3.4.14.5 DPP4 inhibitor Chemical name (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile Parent CAS No. [274901-16-5] Order Size Unit Price Stock 5 mg €95.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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Vildagliptin - NVP-LAF 237Axon 1631 CAS [274901-16-5] MF C17H25N3O2
Description
Highly potent, selective and orally bioavailable inhibitor of dipeptidyl peptidase-4 (DPP4), with IC50 to be 2.3 and 2.7 nM for rat and human plasma DPP4
DPP4 inhibitor
Chemical name(2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile Parent CAS No.[274901-16-5] |
产品资料 |