| 产品名称 | XAV 939 - NVP-XAV 939 |
| 产品货号 | Axon 1527 CAS [284028-89-3] MF C14H11F3N2OSMW 312.31 Purity: 99% Soluble in DMSO Description Tankyrase (TNKS) inhibitor, with IC50 values to be 11 and 4 nM for TNKS1 and TNKS2 respectively; inhibiting Wnt / β-catenin signaling References Certificates Categories Extra info SM Huang et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling. Nature 2009, 461, 614-620. R Nusse. Wnt signaling and stem cell control. Cell Res. 2008, 18, 523-527. RT Peterson, Propping up a destructive regime. Nature 2009, 461, 599–600. EM Adler. Inhibiting Wnt signaling. Sci. Signal. 2009, 2(91), ec326. CE Meacham et al. In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. Nature Gen. 2009, 41(10), 1131-1137. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Stem Cell Wnt-β-Catenin DNA-damage Response EC 2.4.2.30 TNKS Tankyrase (TNKS) inhibitor Chemical name 2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one Parent CAS No. [284028-89-3] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
XAV 939 - NVP-XAV 939Axon 1527 CAS [284028-89-3] MF C14H11F3N2OS
Description
Tankyrase (TNKS) inhibitor, with IC50 values to be 11 and 4 nM for TNKS1 and TNKS2 respectively; inhibiting Wnt / β-catenin signaling
Tankyrase (TNKS) inhibitor
Chemical name2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one Parent CAS No.[284028-89-3] |
| 产品资料 |
