产品名称 | Rolofylline - KW 3902 |
产品货号 | Axon 1603 CAS [136199-02-5] MF C20H28N4O2MW 356.46 Purity: 99% Soluble in DMSO Description Potent and selective adenosine A1 receptor antagonist, with Ki values to be 0.19 nM and 170 nM for A1 and A2 receptors respectively References Certificates Categories Extra info H Nonaka et al. KW-3902, a selective high affinity antagonist for adenosine A1 receptors. Br J Pharmacol. 1996, 117(8), 1645–1652. MM Givertz et al. The effects of KW-3902, an adenosine A1-receptor antagonist, on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance. J. Am. Coll. Cardiol. 2007, 50(16), 1551–60. BM Massie et al. Rolofylline, an Adenosine A1−Receptor Antagonist, in Acute Heart Failure. N. Engl. J. Med. 2010, 363(15), 1419-28. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS A1 A18 Adenosine A1 antagonist Chemical name 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione Parent CAS No. [136199-02-5] Order Size Unit Price Stock 5 mg €85.00 In Stock |
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产品品牌 | axonmedchem |
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Rolofylline - KW 3902Axon 1603 CAS [136199-02-5] MF C20H28N4O2
Description
Potent and selective adenosine A1 receptor antagonist, with Ki values to be 0.19 nM and 170 nM for A1 and A2 receptors respectively
Adenosine A1 antagonist
Chemical name8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione Parent CAS No.[136199-02-5] |
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