产品名称

SB 203580 hydrochloride

产品货号

Axon 1465 CAS [869185-85-3] MF C21H16FN3OS.HClMW 413.90 Purity: 99% Soluble in water Description Potent, cell-permeable and selective inhibitor of p38 MAP kinase (MAPK); water-soluble salt of SB 203580 (Axon 1363) References Certificates Categories Extra info PC Singhal et al. Role of P38 Mitogen-Activated Protein Kinase Phosphorylation and Fas-Fas Ligand Interaction in Morphine-Induced Macrophage Apoptosis. J. Immunol. 2002, 168, 4025-4033. PR Young et al. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J. Biol. Chem. 1997, 272, 12116-12121. H Kankaanranta et al. SB 203580, an Inhibitor of p38 Mitogen-Activated Protein Kinase, Enhances Constitutive Apoptosis of Cytokine-Deprived Human Eosinophils. J. Pharm. Exp. Ther. 1999, 290, 2, 621-628. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Pain & Inflammation Stem Cell MAPK (p38) MAPK EC 2.7.11.24 MAPK inhibitor (p38 specific) Chemical name 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3H-imidazol-4-yl]-pyridine hydrochloride Parent CAS No. [152121-47-6] Order Size Unit Price Stock 5 mg €70.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

SB 203580 hydrochloride

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1465

CAS [869185-85-3]

MF C21H16FN3OS.HCl
MW 413.90

Purity: 99%
Soluble in water

SB 203580 hydrochloride

Description

Potent, cell-permeable and selective inhibitor of p38 MAP kinase (MAPK); water-soluble salt of SB 203580 (Axon 1363)

PC Singhal et al. Role of P38 Mitogen-Activated Protein Kinase Phosphorylation and Fas-Fas Ligand Interaction in Morphine-Induced Macrophage Apoptosis. J. Immunol. 2002, 168, 4025-4033.

PR Young et al. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J. Biol. Chem. 1997, 272, 12116-12121.

H Kankaanranta et al. SB 203580, an Inhibitor of p38 Mitogen-Activated Protein Kinase, Enhances Constitutive Apoptosis of Cytokine-Deprived Human Eosinophils. J. Pharm. Exp. Ther. 1999, 290, 2, 621-628.

MAPK inhibitor (p38 specific)

Chemical name

4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3H-imidazol-4-yl]-pyridine hydrochloride

Parent CAS No.

[152121-47-6]

产品资料