产品名称 MC70 hydrochloride
产品货号 Axon 2591 CAS [N.A.] MF C24H25NO3.HClMW 411.92 Purity: 98% Soluble in DMSO Description Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively), with potential as novel anticancer agent with both cytostatic and cytotoxic characteristics. MC70, as an inhibitor of the ABC transporter ABCB1 (aka MDR1), potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. *Sold in collaboration with Biofordrug srl
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产品品牌 axonmedchem
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MC70 hydrochloride

Based on 43 reference(s) in Google Scholar 9 10 43

Axon 2591

CAS [N.A.]

MF C24H25NO3.HCl
MW 411.92

  • Purity: 98%
  • Soluble in DMSO

MC70 hydrochloride

Description

Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively), with potential as novel anticancer agent with both cytostatic and cytotoxic characteristics. MC70, as an inhibitor of the ABC transporter ABCB1 (aka MDR1), potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment.

*Sold in collaboration with Biofordrug srl

KEYWORDS: MC 70 hydrochloride | supplier | PGP inhibitor | MC70 HCl | CAS [1031367-64-2] | P-glycoprotein | P-GP | Inhibitor | ABC transporter | ABCB1 | MDR1 | BCRP | Caco-2 | breast cancer

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