产品名称

N 6022

产品货号

Axon 1822 CAS [1208315-24-5] MF C24H22N4O3MW 414.46 Purity: 99% Soluble in DMSO Description Potent, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with an IC50 of 8 nM and a Ki of 2.5 nM. Keywords: N 6022 | supplier | GSNOR inhibitor | N6022 | N-6022 | CAS [1208315-24-5] | S-nitrosoglutathione | GSNOR | Inhibitor | Enzymes

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

N 6022

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1822

CAS [1208315-24-5]

MF C24H22N4O3
MW 414.46

Purity: 99%
Soluble in DMSO

N 6022

Description

Potent, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with an IC50 of 8 nM and a Ki of 2.5 nM.

Keywords: N 6022 | supplier | GSNOR inhibitor | N6022 | N-6022 | CAS [1208315-24-5] | S-nitrosoglutathione | GSNOR | Inhibitor | Enzymes

LS Green et al. Mechanism of Inhibition for N6022, a First-in-Class Drug Targeting S-Nitrosoglutathione Reductase. Biochem. 2012, 51(10), 2157-2168.

X Sun et al. Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities. Bioorg. Med. Chem. Lett. 2011, 21(19), 5849-5853.

List of publications using N 6022 (Axon 1822) purchased from Axon Medchem

Cardiovascular Cell Signaling & Oncology Pain & Inflammation GSNOR EC 1.2.1.46

Inhibitor of S-nitrosoglutathione reductase (GSNOR)

Chemical name

3-(5-(4-(1H-imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid

Parent CAS No.

[1208315-24-5]

产品资料