| 产品名称 | PD 169316 |
| 产品货号 | Axon 1365 CAS [152121-53-4] MF C20H13FN4O2MW 360.34 Purity: 99% Soluble in DMSO Description Potent, cell-permeable and selective inhibitor of p38 MAP kinase (MAPK); it blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines References Certificates Categories Extra info DJ. Samuvel et al. A Role for p38 Mitogen-Activated Protein Kinase in the Regulation of the Serotonin Transporter: Evidence for Distinct Cellular Mechanisms Involved in Transporter Surface Expression. J. Neuroscience, 2005, 25(1), 29-41. Y Fu et al. The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor beta-induced Smad signaling in human ovarian cancer cells. Biochem. Biophys. Res. Commun. 2003, 310(2), 391-7. JL Kummer et al. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J. Biol. Chem. 1997, 272(33), 20490-20494. R Nath et al. Inhibition of p38 kinase mimics survival signal-linked protection against apoptosis in rat cerebellar granule neurons. Cell Mol. Biol. Lett. 2001, 6,173-184. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology MAPK (p38) MAPK EC 2.7.11.24 MAPK inhibitor (p38 specific) Chemical name 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine Parent CAS No. [152121-53-4] Order Size Unit Price Stock 2 mg €50.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
PD 169316Axon 1365 CAS [152121-53-4] MF C20H13FN4O2
Description
Potent, cell-permeable and selective inhibitor of p38 MAP kinase (MAPK); it blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines
MAPK inhibitor (p38 specific)
Chemical name4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine Parent CAS No.[152121-53-4] |
| 产品资料 |
