| 产品名称 | BIX 02189 |
| 产品货号 | Axon 1809 CAS [1094614-85-3] MF C27H28N4O2MW 440.54 Purity: 99% Soluble in DMSO Description Selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively References Certificates Categories Extra info RJ Tatake et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem. Biophys. Res. Comm. 2008, 377(1), 120–125. Y Obara and N Nakahata. The signaling pathway leading to extracellular signal-regulated kinase 5 (ERK5) activation via G-proteins and ERK5-dependent neurotrophic effects. Mol. Pharmacol. 2010, 77(1), 10-16. BA Drew, ME Burowa , BS Beckman. MEK5/ERK5 pathway: The first fifteen years. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2012, 1825 (1), 37-48. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell MAPK EC 2.7.12.2 ERK MEK MEK5 inhibitor; ERK5 inhibitor Chemical name ((3-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide Parent CAS No. [1094614-85-3 1265916-41-3 (Z-isomer)] Order Size Unit Price Stock 5 mg €125.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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| 产品详情 |
BIX 02189Axon 1809 CAS [1094614-85-3] MF C27H28N4O2
Description
Selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively
MEK5 inhibitor; ERK5 inhibitor
Chemical name((3-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide Parent CAS No.[1094614-85-3 1265916-41-3 (Z-isomer)] |
| 产品资料 |
