| 产品名称 | FR 180204 |
| 产品货号 | Axon 1694 CAS [865362-74-9] MF C18H13N7MW 327.34 Purity: 99% Soluble in DMSO Description Selective, cell permeable and ATP-competitive ERK inhibitor; 30-fold selective on ERK over p38α MAPK; FR180204 was shown to inhibit ERK1 (Ki=0.31μM), ERK2 (Ki=0.14 μM) and TGFβ-induced AP-1 activation References Certificates Categories Extra info M Ohori et al. Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. Biochem Biophys Res Commun. 2005, 336(1), 357-363. M Ohori. ERK inhibitors as a potential new therapy for rheumatoid arthritis. Drug News Perspect. 2008, 21(5), 245-250. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Transcription Factors MAPK PI3K-Akt-mTOR EC 2.7.11.24 ERK ERK inhibitor; AP-1 inhibitor Chemical name 3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine Parent CAS No. [865362-74-9] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
FR 180204Axon 1694 CAS [865362-74-9] MF C18H13N7
Description
Selective, cell permeable and ATP-competitive ERK inhibitor; 30-fold selective on ERK over p38α MAPK; FR180204 was shown to inhibit ERK1 (Ki=0.31μM), ERK2 (Ki=0.14 μM) and TGFβ-induced AP-1 activation
ERK inhibitor; AP-1 inhibitor
Chemical name3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine Parent CAS No.[865362-74-9] |
| 产品资料 |
