| 产品名称 | LB 42708 |
| 产品货号 | Axon 1794 CAS [226929-39-1] MF C30H27BrN4O2MW 555.46 Purity: 99% Soluble in DMSO Description Selective and orally available inhibitor of farnesyltransferase (FTase), with IC50 values of 0.8 nM in vitro and 8 nM in cultured cells against p21-ras farnesylation References Certificates Categories Extra info HJ Na et al. Inhibition of Farnesyltransferase Prevents Collagen-Induced Arthritis by Down-Regulation of Inflammatory Gene Expression through Suppression of p21ras-Dependent NF-κB Activation. J. Immunol. 2004, 173, 1276-1283. CK Kim et al. The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting Ras-dependent mitogen-activated protein kinase and PI3K/Akt signal pathways. Mol. Pharmacol. 2010, 78, 142-150. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Farnesyltransferase EC 2.5.1.58 Inhibitor of farnesyltransferase (FTase) Chemical name (1-((1-(4-bromobenzyl)-1H-imidazol-5-yl)methyl)-4-(naphthalen-1-yl)-1H-pyrrol-3-yl)(morpholino)methanone Parent CAS No. [226929-39-1] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
LB 42708Axon 1794 CAS [226929-39-1] MF C30H27BrN4O2
Description
Selective and orally available inhibitor of farnesyltransferase (FTase), with IC50 values of 0.8 nM in vitro and 8 nM in cultured cells against p21-ras farnesylation
Inhibitor of farnesyltransferase (FTase)
Chemical name(1-((1-(4-bromobenzyl)-1H-imidazol-5-yl)methyl)-4-(naphthalen-1-yl)-1H-pyrrol-3-yl)(morpholino)methanone Parent CAS No.[226929-39-1] |
| 产品资料 |
