产品名称

AT 406 - SM 406

产品货号

Axon 1985 CAS [1071992-99-8] MF C32H43N5O4MW 561.71 Purity: 100% Optical purity: Optically pure Soluble in DMSO Description Potent and orally available antagonist of the inhibitor of apoptosis proteins (IAPs); binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively References Certificates Categories Extra info Q Cai et al. A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. J. Med. Chem. 2011, 54 (8), 2714–2726. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology IAP Antagonist of Inhibitor of apoptosis proteins (IAPs) Chemical name (5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide Parent CAS No. [1071992-99-8] Order Size Unit Price Stock 5 mg €145.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

AT 406 - SM 406

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1985

CAS [1071992-99-8]

MF C32H43N5O4
MW 561.71

Purity: 100%
Optical purity: Optically pure
Soluble in DMSO

AT 406

Description

Potent and orally available antagonist of the inhibitor of apoptosis proteins (IAPs); binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively

Q Cai et al. A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment. J. Med. Chem. 2011, 54 (8), 2714–2726.

Antagonist of Inhibitor of apoptosis proteins (IAPs)

Chemical name

(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide

Parent CAS No.

[1071992-99-8]

产品资料