产品名称 DG2 - S6K1 Inhibitor DG2
产品货号 Axon 1903 CAS [871340-88-4] MF C16H17BrN6OMW 389.25 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1) (IC50: 9.1 nM for S6K1); no Akt activity (IC50: 22000 nM); ATP-competitive and cell-permeable References Certificates Categories Extra info T Okuzumi et al. Inhibitor Hijacking of Akt Activation. Nat. Chem. Biol. 2009, 5(7), 484–493.   BT Wang et al. The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile. PNAS 2011, 108 (37), 15201-15206. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK PI3K-Akt-mTOR EC 2.7.11.1 p70-RSK RSK inhibitor (p70 ribosomal S6 kinase 1 specific) Chemical name 3-bromo-4-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine Parent CAS No. [871340-88-4] Order Size Unit Price Stock 10 mg €95.00 In Stock
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DG2 - S6K1 Inhibitor DG2

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1903

CAS [871340-88-4]

MF C16H17BrN6O
MW 389.25

  • Purity: 99%
  • Soluble in DMSO

DG2

Description

Potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1) (IC50: 9.1 nM for S6K1); no Akt activity (IC50: 22000 nM); ATP-competitive and cell-permeable
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