产品名称

AZD 5363 dihydrochloride - Capivasertib

产品货号

Axon 1859 CAS [2108875-84-7] MF C21H25ClN6O2.2HClMW 501.84 Purity: 99% Soluble in water and DMSO Description Orally bioavailable, selective and potent protein kinase B (Akt) inhibitor in low nM potency; AZD5363 dihydrochloride is directly water-soluble. KEYWORDS: AZD 5363 dihydrochloride | supplier | Akt inhibitor | Capivasertib | AZD5363 | AZD-5363 | CAS [1143532-39-1] | Axon Medchem | Axon 1859 | Phosphatidylinositol | Akt | Inhibitor | Enzymes

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

AZD 5363 dihydrochloride - Capivasertib

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1859

CAS [2108875-84-7]

MF C21H25ClN6O2.2HCl
MW 501.84

Purity: 99%
Soluble in water and DMSO

AZD 5363 dihydrochloride

Description

Orally bioavailable, selective and potent protein kinase B (Akt) inhibitor in low nM potency; AZD5363 dihydrochloride is directly water-soluble.

KEYWORDS: AZD 5363 dihydrochloride | supplier | Akt inhibitor | Capivasertib | AZD5363 | AZD-5363 | CAS [1143532-39-1] | Axon Medchem | Axon 1859 | Phosphatidylinositol | Akt | Inhibitor | Enzymes

BR Davies et al. Preclinical Pharmacology of AZD5363, an Orally Bioavailable Inhibitor of AKT: Pharmacodynamics, Antitumor Activity and Correlation of Monotherapy Activity with Genetic Background. Mol. Cancer Ther. 2012, 11(4), 873-887.

Cell Signaling & Oncology Akt PI3K-Akt-mTOR EC 2.7.11.1

Inhibitor of protein kinase B (Akt)

Chemical name

(S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide dihydrochloride

Parent CAS No.

[1143532-39-1]

产品资料