产品名称 PHT 427
产品货号 Axon 1870 CAS [1191951-57-1] MF C20H31N3O2S2MW 409.61 Purity: 99% Soluble in DMSO Description Inhibitor of AKT and phosphoinositide-dependent protein kinase 1 (PDPK1 or PDK1). PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity References Certificates Categories Extra info EJ Meuillet et al. Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor. Mol. Cancer Ther. 2010, 9, 706.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Akt PI3K-Akt-mTOR EC 2.7.11.1 PDPK Inhibitor of Akt and PDPK1 Chemical name 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide Parent CAS No. [1191951-57-1] Order Size Unit Price Stock 10 mg €75.00 In Stock
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PHT 427

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1870

CAS [1191951-57-1]

MF C20H31N3O2S2
MW 409.61

  • Purity: 99%
  • Soluble in DMSO

PHT 427

Description

Inhibitor of AKT and phosphoinositide-dependent protein kinase 1 (PDPK1 or PDK1). PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity
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