| 产品名称 | PF 4708671 - PF 04708671 |
| 产品货号 | Axon 1602 CAS [1255517-76-0] MF C19H21F3N6MW 390.41 Purity: 99% Soluble in DMSO Description Highly specific and cell-permeable p70 ribosomal S6 kinase (S6K1) inhibitor with Ki of 20 nM and IC50 of 160 nM; having no effect on the closely related RSK and MSK kinases; Useful tool for delineating S6K1-specific roles downstream of mTOR References Certificates Categories Extra info LR Pearce et al. Characterisation of PF-4708671 a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). Biochem. J. 2010, 431, 245-255. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK PI3K-Akt-mTOR EC 2.7.11.1 p70-RSK Pfizer Licensed Products RSK inhibitor (p70 RSK specific) Chemical name 2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1255517-76-0] Order Size Unit Price Stock 10 mg €110.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
PF 4708671 - PF 04708671Axon 1602 CAS [1255517-76-0] MF C19H21F3N6
Description
Highly specific and cell-permeable p70 ribosomal S6 kinase (S6K1) inhibitor with Ki of 20 nM and IC50 of 160 nM; having no effect on the closely related RSK and MSK kinases; Useful tool for delineating S6K1-specific roles downstream of mTOR
RSK inhibitor (p70 RSK specific)
Chemical name2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[1255517-76-0] |
| 产品资料 |
