产品名称

Thiazovivin - TZV

产品货号

Axon 1535 CAS [1226056-71-8] MF C15H13N5OSMW 311.36 Purity: 99% Soluble in DMSO Description A small molecule that enhances the survival of human embryonic stem cells (hESCs) after trypsinzation; ROCK inhibitor; Thiazovivin dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, when used in combination with ALK5 inhibitor SB 431542 (Axon 1661) and MEK inhibitor PD 0325091 (Axon 1408) *Promotion

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Thiazovivin - TZV

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1535

CAS [1226056-71-8]

MF C15H13N5OS
MW 311.36

Purity: 99%
Soluble in DMSO

Thiazovivin

Description

A small molecule that enhances the survival of human embryonic stem cells (hESCs) after trypsinzation; ROCK inhibitor; Thiazovivin dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, when used in combination with ALK5 inhibitor SB 431542 (Axon 1661) and MEK inhibitor PD 0325091 (Axon 1408)

*Promotion: Thiazovivin is also part of Inhibitor Set(s):

Axon 5009

T Lin and S Ding et al. A chemical platform for improved induction of human iPSCs. Nat. Methods. 2009, 6(11), 805-8.

Y Xu and S Ding et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc. Natl. Acad. Sci. USA 2010, 107, 8129.

ROCK inhibitor and iPSC stimulator; Stem cell related

Chemical name

N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide

Parent CAS No.

[1226056-71-8]

产品资料