| 产品名称 | AM 095 (parent compound) |
| 产品货号 | Axon 2367 CAS [1228690-36-5] MF C27H24N2O5MW 456.49 Purity: 99% Optical purity: Optically pure Soluble in 0.1N NaOH(aq) and DMSO Description A novel potent and selective LPA1 antagonist (IC50 values 0.025 μM and 0.023 μM for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells,respectively). AM 095 attenuates bleomycin-induced dermal fibrosis. References Certificates Categories Extra info F.V. Castelino et al. Genetic deletion or pharmacologic antagonism of LPA1 ameliorates dermal fibrosis in a scleroderma mouse model. Arthritis Rheum. 2011, 63, 1405-1415. Certificate of Analysis Material Safety Data Sheet Pain & Inflammation A13 LPA1 Novel potent and selective LPA1 antagonist Chemical name (R)-2-(4'-(3-methyl-4-((1-phenylethoxy)carbonylamino)isoxazol-5-yl)biphenyl-4-yl)acetic acid Parent CAS No. [1228690-36-5] Order Size Unit Price Stock 10 mg €125.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
AM 095 (parent compound)Axon 2367 CAS [1228690-36-5] MF C27H24N2O5
DescriptionA novel potent and selective LPA1 antagonist (IC50 values 0.025 μM and 0.023 μM for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells,respectively). AM 095 attenuates bleomycin-induced dermal fibrosis.
Novel potent and selective LPA1 antagonist
Chemical name(R)-2-(4'-(3-methyl-4-((1-phenylethoxy)carbonylamino)isoxazol-5-yl)biphenyl-4-yl)acetic acid Parent CAS No.[1228690-36-5] |
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