产品名称 | SKI II - SKI 2 |
产品货号 | Axon 2782 CAS [312636-16-1] MF C15H11ClN2OSMW 302.78 Purity: 99% Soluble in DMSO Description SKI II is an orally bioavailable sphingosine kinase (SK or SphK) inhibitor (IC50 value of 0.5 µM) without competition at the ATP-binding site of SK. Moreover, SKI II showed no inhibition on a small panel of human protein kinases (ERK2 and PKC-α) and a lipid kinase (PI3K). SKI II inhibited cancer cell proliferation, induced apoptosis and inhibited tumor growth in mice. KEYWORDS: SKI II | supplier | SphK inhibitor | SKI 2 | SKIII | SKI-II | SKI2 | SKI-2 | CAS [312636-16-1] | Sphingosine | SphK1 | SphK2 | Inhibitor | Enzymes | Apoptosis |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
SKI II - SKI 2Axon 2782 CAS [312636-16-1] MF C15H11ClN2OS
DescriptionSKI II is an orally bioavailable sphingosine kinase (SK or SphK) inhibitor (IC50 value of 0.5 µM) without competition at the ATP-binding site of SK. Moreover, SKI II showed no inhibition on a small panel of human protein kinases (ERK2 and PKC-α) and a lipid kinase (PI3K). SKI II inhibited cancer cell proliferation, induced apoptosis and inhibited tumor growth in mice. KEYWORDS: SKI II | supplier | SphK inhibitor | SKI 2 | SKIII | SKI-II | SKI2 | SKI-2 | CAS [312636-16-1] | Sphingosine | SphK1 | SphK2 | Inhibitor | Enzymes | Apoptosis
Orally bioavailable SphK inhibitor
Chemical name4-(4-(4-Chlorophenyl)thiazol-2-ylamino)phenol Parent CAS No.[312636-16-1] |
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