产品名称

Tiplaxtinin - PAI 039

产品货号

Axon 1383 CAS [393105-53-8] MF C24H16F3NO4MW 439.38 Purity: 99% Soluble in DMSO Description Inhibitor of plasminogen activator inhibitor-1 (PAI-1). KEYWORDS: Tiplaxtinin | supplier | PAI-1 inhibitor | PAI 039 | PAI039 | PAI-039 | CAS [393105-53-8] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | thrombosis | diabetes

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Tiplaxtinin - PAI 039

Based on 56 publications in PubMed 10 10 56

Axon 1383

CAS [393105-53-8]

MF C24H16F3NO4
MW 439.38

Purity: 99%
Soluble in DMSO

Tiplaxtinin

Description

Inhibitor of plasminogen activator inhibitor-1 (PAI-1).

KEYWORDS: Tiplaxtinin | supplier | PAI-1 inhibitor | PAI 039 | PAI039 | PAI-039 | CAS [393105-53-8] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | thrombosis | diabetes

JK Hennan et al. Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid], a novel plasminogen activator inhibitor-1 inhibitor, in a canine model of coronary artery thrombosis. J. Ph. Exp. Ther. 2005, 314(2), 710-6.

H Elokdah et al. Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1: Design, Synthesis, and Preclinical Characterization. J. Med. Chem. 2004, 47, 3491-3494.

JK Hennan et al. Effect of Tiplaxtinin (PAI-039), an orally bioavailable PAI-1 antagonist, in a rat model of thrombosis. J. Throm. Haem. 2008, 6(9), 1558-1564.

MP Krause et al. Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice. Diabetes, 2011, 60(7), 1964-1972.

List of publications using Tiplaxtinin (Axon 1383) purchased from Axon Medchem

Cardiovascular Miscellaneous Plasminogen activator inhibitor-1 (PAI-1) EC 3.4.21

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Chemical name

[1-Benzyl-5-(4-trifluoromethoxy-phe nyl)-1H-indol-3-yl]-oxo-acetic acid

Parent CAS No.

[393105-53-8]

产品资料