产品名称 | SEW 2871 |
产品货号 | Axon 1672 CAS [256414-75-2] MF C20H10F6N2OSMW 440.36 Purity: 100% Soluble in DMSO Description Potent, cell-permeable and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist (EC50: 13 nM); Does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM References Certificates Categories Extra info JJ Hale et al. A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists. J. Med. Chem. 2004, 47 6662. MG Sanna et al. Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate. J. Biol. Chem. 2004, 279 13839. Certificate of Analysis Material Safety Data Sheet Angiogenesis Apoptosis Cardiovascular Immunology Miscellaneous S1PR1 A13 S1PR1 agonist Chemical name 5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole Parent CAS No. [256414-75-2] Order Size Unit Price Stock 10 mg €75.00 In Stock |
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产品品牌 | axonmedchem |
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SEW 2871Axon 1672 CAS [256414-75-2] MF C20H10F6N2OS
Description
Potent, cell-permeable and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist (EC50: 13 nM); Does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM
S1PR1 agonist
Chemical name5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole Parent CAS No.[256414-75-2] |
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