产品名称

CoPo 22

产品货号

Axon 1763 CAS [606101-83-1] MF C22H22N4O2MW 374.44 Purity: 99% Soluble in DMSO Description Corrector and potentiator (Co-Po) for ∆F508-cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel function in cystic fibrosis, with low micromolar EC50 References Certificates Categories Extra info PW Phuan et al. Cyanoquinolines with Independent Corrector and Potentiator Activities Restore ∆F508-CFTR Chloride Channel Function in Cystic Fibrosis. Mol. Pharmacol. 2011, 80(4), 683-693. AS Verkman et al. CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr. Pharm. Des. 2006; 12(18), 2235-2247. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CFTR EC 3.6.3.49 Modulator of CFTR (δ-F508 Selective) Chemical name N-(2-(3-cyano-5,7-dimethylquinolin-2-ylamino)ethyl)-3-methoxybenzamide Parent CAS No. [606101-83-1] Order Size Unit Price Stock 5 mg €120.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

CoPo 22

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1763

CAS [606101-83-1]

MF C22H22N4O2
MW 374.44

Purity: 99%
Soluble in DMSO

CoPo 22

Description

Corrector and potentiator (Co-Po) for ∆F508-cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel function in cystic fibrosis, with low micromolar EC50

PW Phuan et al. Cyanoquinolines with Independent Corrector and Potentiator Activities Restore ∆F508-CFTR Chloride Channel Function in Cystic Fibrosis. Mol. Pharmacol. 2011, 80(4), 683-693.

AS Verkman et al. CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr. Pharm. Des. 2006; 12(18), 2235-2247.

Modulator of CFTR (δ-F508 Selective)

Chemical name

N-(2-(3-cyano-5,7-dimethylquinolin-2-ylamino)ethyl)-3-methoxybenzamide

Parent CAS No.

[606101-83-1]

产品资料