| 产品名称 | IBP, 4- - NSC 667672 |
| 产品货号 | Axon 2919 CAS [155798-08-6] MF C19H21IN2OMW 420.29 Purity: 98% Soluble in DMSO Description 4-IBP is a selective sigma-1 (σ-1) agonist with Ki values of 1.70 nM and 25.2 nM for σ-1 and σ-2 receptor subtypes, respectively. Activating the σ-1 receptor with noncytotoxic doses of 4-IBP decreases the migration levels of various types of cancer cells, including C32 melanoma, U373-MG glioblastoma, A549 NSCLC, and PC3 prostate cancer cells. Moreover, 4-IBP sensitizes these cancer cells in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. KEYWORDS: 4-IBP | supplier | Sigma-1 agonist | NSC 667672 | 4IBP | 4 IBP | NSC667672 | NSC-667672 | CAS [155798-08-6] | Sigma Receptor Substrates | Sigma-1 | Antagonist | Receptors |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
IBP, 4- - NSC 667672Axon 2919 CAS [155798-08-6] MF C19H21IN2O
Description4-IBP is a selective sigma-1 (σ-1) agonist with Ki values of 1.70 nM and 25.2 nM for σ-1 and σ-2 receptor subtypes, respectively. Activating the σ-1 receptor with noncytotoxic doses of 4-IBP decreases the migration levels of various types of cancer cells, including C32 melanoma, U373-MG glioblastoma, A549 NSCLC, and PC3 prostate cancer cells. Moreover, 4-IBP sensitizes these cancer cells in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. KEYWORDS: 4-IBP | supplier | Sigma-1 agonist | NSC 667672 | 4IBP | 4 IBP | NSC667672 | NSC-667672 | CAS [155798-08-6] | Sigma Receptor Substrates | Sigma-1 | Antagonist | Receptors
Selective sigma-1 (σ-1) receptor agonist
Chemical nameN-(1-Benzylpiperidin-4-yl)-4-iodobenzamide Parent CAS No.[155798-08-6] |
| 产品资料 |
