产品名称 | HMR 1098 - HMR 1883 sodium salt |
产品货号 | Axon 1757 CAS [261717-22-0] MF C19H21ClN3NaO5S2MW 493.96 Purity: 98% Soluble in water and DMSO Description KATP channel blocker; HMR 1098 acts by inactivating the ATP-sensitive potassium channels (KATP) responsible for potassium efflux. HMR 1098 is an inhibitor of Kir6.2/SUR1-composed K(ATP) channels References Certificates Categories Extra info H Gögelein et al. Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion. N. Schmiedebergs Arch Pharmacol. 2001, 364(1), 33-41. HX ZHang et al. HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels. J. Mol. Cell Cardiol. 2011, 50(3), 552-560. Certificate of Analysis Material Safety Data Sheet Cardiovascular Cell Signaling & Oncology CNS Diabetes & Metabolism KCNJ11 Kir6.2-SUR1 K+ channel blocker (SUR1/Kir6.2 selective) Chemical name sodium (5-chloro-2-methoxybenzoyl)(4-methoxy-3-(N-(methylcarbamothioyl)sulfamoyl)phenethyl)amide Parent CAS No. [158751-64-5] Order Size Unit Price Stock 5 mg €115.00 In Stock |
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产品品牌 | axonmedchem |
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HMR 1098 - HMR 1883 sodium saltAxon 1757 CAS [261717-22-0] MF C19H21ClN3NaO5S2
Description
KATP channel blocker; HMR 1098 acts by inactivating the ATP-sensitive potassium channels (KATP) responsible for potassium efflux. HMR 1098 is an inhibitor of Kir6.2/SUR1-composed K(ATP) channels
K+ channel blocker (SUR1/Kir6.2 selective)
Chemical namesodium (5-chloro-2-methoxybenzoyl)(4-methoxy-3-(N-(methylcarbamothioyl)sulfamoyl)phenethyl)amide Parent CAS No.[158751-64-5] |
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