产品名称

AC 264613

产品货号

Axon 2898 CAS [1051487-82-1] MF C19H18BrN3O2MW 400.27 Purity: 98% Soluble in DMSO Recently added

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

AC 264613

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2898

CAS [1051487-82-1]

MF C19H18BrN3O2
MW 400.27

Purity: 98%
Soluble in DMSO

Recently added

AC 264613

Description

AC 264613 is a potent, selective, and metabolically stable protease activated receptor 2 (PAR2) agonist (pEC50 value of 6.7). The potency of AC 264613 in the cellular proliferation assay was approximately 50 nM, and was virtually the same at wild-type PAR2 receptors. Incubation of macrophages with AC 264613 caused a decrease of IRF5 expression and also significantly reduced p53 protein expression.