| 产品名称 | Q94 hydrochloride |
| 产品货号 | Axon 2055 CAS [1052076-77-3] MF C21H17ClN2.HClMW 369.29 Purity: 99% Soluble in DMSO Description PAR1/Gαq-specific allosteric inhibitor or negative allosteric modulator (NAM); Q94 selectively blocks PAR1/Gαq interaction and signalling References Certificates Categories Extra info X Ding et al. Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Gαq and cooperation between ERK1/2 and Rho kinase signaling pathways. Mol. Biol. Cell, 2008, 19(6), 2520-2533. S Asteriti et al. Modulation of PAR1 signalling by benzimidazole compounds. Br. J. Pharmacol. 2012, 167, 80–94. PF Mercer et al. Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1–inducible CCL2 in Pulmonary Fibrosis. Am. J. Resp. Critical Care Med. 2009, 179(5), 414-425. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology A15 Thrombin (PAR) Negative allosteric modulator of PAR1 (Gαq linkage) Chemical name 2-benzyl-1-(4-chlorobenzyl)-1H-benzo[d]imidazole hydrochloride Parent CAS No. [537009-12-4] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
Q94 hydrochlorideAxon 2055 CAS [1052076-77-3] MF C21H17ClN2.HCl
Description
PAR1/Gαq-specific allosteric inhibitor or negative allosteric modulator (NAM); Q94 selectively blocks PAR1/Gαq interaction and signalling
Negative allosteric modulator of PAR1 (Gαq linkage)
Chemical name2-benzyl-1-(4-chlorobenzyl)-1H-benzo[d]imidazole hydrochloride Parent CAS No.[537009-12-4] |
| 产品资料 |
