产品名称

SLV 319, rac-(±)-

产品货号

Axon 1712 CAS [362519-49-1] MF C23H20Cl2N4O2SMW 487.40 Purity: 99% Soluble in DMSO Description Racemate of the potent and highly selective CB1 antagonist Ibipinabant (Axon 1713, Ki value 25 nM and >1000 nM for CB1 and CB2, respectively). References Certificates Categories Extra info JH Lange etal. Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists. J. Med. Chem. 2004, 47(3), 627–643. JH Lange and CG Kruse. Recent advances in CB1 cannabinoid receptor antagonists. Curr. Opin. Drug Discov. Devel. 2004, 7(4), 498-506. AB Need et al. The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats. Psychopharmacol. 2006, 184(1), 26–35. JH Lange et al. Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor.... J. Med. Chem. 2010, 53, 1338-1346. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS Diabetes & Metabolism Pain & Inflammation CB1 A13 Racemate of CB1 antagonist Ibipinabant (Axon 1713) Chemical name 3-(4-chlorophenyl)-N'-(4-chlorophenylsulfonyl)-N-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide Parent CAS No. [362519-49-1] Order Size Unit Price Stock 5 mg €110.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

SLV 319, rac-(±)-

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1712

CAS [362519-49-1]

MF C23H20Cl2N4O2S
MW 487.40

Purity: 99%
Soluble in DMSO

SLV 319, rac-(±)-

Description

Racemate of the potent and highly selective CB1 antagonist Ibipinabant (Axon 1713, Ki value 25 nM and >1000 nM for CB1 and CB2, respectively).

JH Lange etal. Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists. J. Med. Chem. 2004, 47(3), 627–643.

JH Lange and CG Kruse. Recent advances in CB1 cannabinoid receptor antagonists. Curr. Opin. Drug Discov. Devel. 2004, 7(4), 498-506.

AB Need et al. The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats. Psychopharmacol. 2006, 184(1), 26–35.

JH Lange et al. Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor.... J. Med. Chem. 2010, 53, 1338-1346.

Racemate of CB1 antagonist Ibipinabant (Axon 1713)

Chemical name

3-(4-chlorophenyl)-N'-(4-chlorophenylsulfonyl)-N-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide

Parent CAS No.

[362519-49-1]

产品资料