产品名称 | AMD 3100 - Plerixafor | SID 791 | JM 3100 |
产品货号 | Axon 1738 CAS [155148-31-5] MF C28H54N8.8HClMW 794.47 Purity: 100% Soluble in water Description Highly potent and selective chemokine CXCR4 receptor antagonist, with IC50 values to be 0.02-0.13 and >25 μM for CXCR4 and all other chemokine receptors respectively); HIV inhibitor; an immunostimulant used to multiply hematopoietic stem cells in cancer patients References Certificates Categories Extra info E De Clercq et al. Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100. Antimicrob. agents chemother. 1994, 38(4), 668–74. SL Davies et al. Plerixafor Hydrochloride. Drugs Fut. 2007, 32(2), 123. AF Cashen et al. AMD3100: CXCR4 antagonist and rapid stem cell-mobilizing agent. Future Oncol. 2007, 3(1), 19–27. G Calandra et al. AMD3100 plus G-CSF can successfully mobilize CD34+ cells from non-Hodgkin's lymphoma, Hodgkin's disease and multiple myeloma patients previously failing mobilization with chemotherapy (...). Bone Marrow Transpl. 2008, 41, 331–338. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology Stem Cell Immunomodulator A2 Chemokine CXCR4 antagonist Chemical name 1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene octahydrochloride Parent CAS No. [110078-46-1] Order Size Unit Price Stock 10 mg €85.00 In Stock |
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产品品牌 | axonmedchem |
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AMD 3100 - Plerixafor | SID 791 | JM 3100Axon 1738 CAS [155148-31-5] MF C28H54N8.8HCl
Description
Highly potent and selective chemokine CXCR4 receptor antagonist, with IC50 values to be 0.02-0.13 and >25 μM for CXCR4 and all other chemokine receptors respectively); HIV inhibitor; an immunostimulant used to multiply hematopoietic stem cells in cancer patients
CXCR4 antagonist
Chemical name1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene octahydrochloride Parent CAS No.[110078-46-1] |
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