产品名称

CNV 1014802 - GSK 1014802 | GSK2 | Raxatrigine | BIIB 074 | Vixotrigine

产品货号

Axon 1899 CAS [934240-30-9] MF C18H19FN2O2MW 314.35 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Sodium channel blocker with potent anticonvulsant activity; potential for novel treatment for Schizophrenia. CNV 1014802 (GSK 1014802 or GSK2 or Raxatrigine) was tested in clinical trials for treatment of trigeminal neuralgia, and shows selectivity for the Nav1.7 subtype over the other subtypes tested (Nav1.1, Nav1.2, Nav1.3, Nav1.5, Nav1.6 and TTX-R), for both the resting and depolarized states. The water soluble HCl salt of CNV 1014802 (Axon 2548) is available as well KEYWORDS: CNV 1014802 | supplier | Na+ channel blocker | GSK 1014802 | GSK2 | Raxatrigine | BIIB 074 | Vixotrigine | CNV1014802 | CNV-1014802 | GSK1014802 | GSK-1014802 | GSK 2 | GSK-2 | BIIB074 | BIIB-074 | CAS [934240-30-9] | Sodium | Nav1.7 | Nav1.2 | Nav1.6 | Nav1.3 | Blocker | Ion Channels | anticonvulsant | Schizophrenia | trigeminal neuralgia | neuropathic | pain

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

CNV 1014802 - GSK 1014802 | GSK2 | Raxatrigine | BIIB 074 | Vixotrigine

Based on 56 reference(s) in Google Scholar 9 10 56

Axon 1899

CAS [934240-30-9]

MF C18H19FN2O2
MW 314.35

Purity: 99%
Optical purity: Optically pure
Soluble in 0.1N HCl(aq) and DMSO

CNV 1014802

Description

Sodium channel blocker with potent anticonvulsant activity; potential for novel treatment for Schizophrenia. CNV 1014802 (GSK 1014802 or GSK2 or Raxatrigine) was tested in clinical trials for treatment of trigeminal neuralgia, and shows selectivity for the Nav1.7 subtype over the other subtypes tested (Nav1.1, Nav1.2, Nav1.3, Nav1.5, Nav1.6 and TTX-R), for both the resting and depolarized states.

The water soluble HCl salt of CNV 1014802 (Axon 2548) is available as well

KEYWORDS: CNV 1014802 | supplier | Na+ channel blocker | GSK 1014802 | GSK2 | Raxatrigine | BIIB 074 | Vixotrigine | CNV1014802 | CNV-1014802 | GSK1014802 | GSK-1014802 | GSK 2 | GSK-2 | BIIB074 | BIIB-074 | CAS [934240-30-9] | Sodium | Nav1.7 | Nav1.2 | Nav1.6 | Nav1.3 | Blocker | Ion Channels | anticonvulsant | Schizophrenia | trigeminal neuralgia | neuropathic | pain