产品名称 Nav1.7 blocker 24 - Compound 24
产品货号 Axon 1791 CAS [1315451-25-2] MF C20H16Cl2F3N3O3MW 474.26 Purity: 99% Soluble in DMSO Description Sodium channel blocker, potent and selective at voltage-gated Nav1.7 (SCN9A); with Nav1.7 pIC50 6.75 and Nav1.5 pIC50 <4.48 References Certificates Categories Extra info I Macsari et al. Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship. Bioorg. Med. Chem. Lett. 2011, 21(13), 3871-3876.  Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation Nav1.7 Unclassified Nav1.7 blocker Chemical name 2-(3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)-N-((6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)acetamide Parent CAS No. [1315451-25-2] Order Size Unit Price Stock 10 mg €125.00 In Stock
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Nav1.7 blocker 24 - Compound 24

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1791

CAS [1315451-25-2]

MF C20H16Cl2F3N3O3
MW 474.26

  • Purity: 99%
  • Soluble in DMSO

Nav1.7 blocker 24

Description

Sodium channel blocker, potent and selective at voltage-gated Nav1.7 (SCN9A); with Nav1.7 pIC50 6.75 and Nav1.5 pIC50 <4.48
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