产品名称

A 803467

产品货号

Axon 1915 CAS [944261-79-4] MF C19H16ClNO4MW 357.79 Purity: 98% Soluble in DMSO Description Sodium channel blocker, potent and selective at voltage-gated Nav1.8 channel (IC50: 8 nM). KEYWORDS: A 803467 | supplier | Nav1.8 blocker | A803467 | A-803467 | CAS [944261-79-4] | Sodium | Nav1.8 | Blocker | Ion Channels

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

A 803467

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1915

CAS [944261-79-4]

MF C19H16ClNO4
MW 357.79

Purity: 98%
Soluble in DMSO

A 803467

Description

Sodium channel blocker, potent and selective at voltage-gated Nav1.8 channel (IC50: 8 nM).

KEYWORDS: A 803467 | supplier | Nav1.8 blocker | A803467 | A-803467 | CAS [944261-79-4] | Sodium | Nav1.8 | Blocker | Ion Channels

MF Jarvis et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc. Natl. Acad. Sci. 2007, 104(20), 8520-8525.

S McGaraughty et al. A Selective Nav1.8 Sodium Channel Blocker, A-803467 [5-(4-Chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], Attenuates Spinal Neuronal Activity in Neuropathic Rats. J. Pharmacol. Exp. Ther. 2008, 324(3), 1204-1211.

CNS Pain & Inflammation Nav1.8 Unclassified

Blocker of the voltage-gated Nav1.8 channel

Chemical name

5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide

Parent CAS No.

[944261-79-4]

产品资料