产品名称 Nav1.7 blocker 52 - Compound 52
产品货号 Axon 1780 CAS [1211866-85-1] MF C25H27F3N6O3MW 516.52 Purity: 99% Soluble in DMSO Description Potent and state-dependent sodium channel blocker, selective at voltage-gated Nav1.7 (SCN9A); Selectivity over many ion channels and GPCRs, including some selectivity within the sodium channel family References Certificates Categories Extra info H Bregman et al. Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain. J. Med. Chem. 2011, 54(13), 4427-4445. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation Nav1.7 Unclassified Nav1.7 blocker Chemical name N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide Parent CAS No. [1211866-85-1] Order Size Unit Price Stock 10 mg €125.00 In Stock
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Nav1.7 blocker 52 - Compound 52

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1780

CAS [1211866-85-1]

MF C25H27F3N6O3
MW 516.52

  • Purity: 99%
  • Soluble in DMSO

Nav1.7 blocker 52

Description

Potent and state-dependent sodium channel blocker, selective at voltage-gated Nav1.7 (SCN9A); Selectivity over many ion channels and GPCRs, including some selectivity within the sodium channel family
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