| 产品名称 | Selisistat - EX 527 |
| 产品货号 | Axon 1956 CAS [49843-98-3] MF C13H13ClN2OMW 248.71 Purity: 99% Soluble in DMSO Description Potent and selective deacetylase sirtin 1 (SIRT1) inhibitor; a useful tool for studying the relationship between SIRT1 and cell regulation; a potential agent the treatment of Huntington’s Disease (HD) References Certificates Categories Extra info AD Napper et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J. Med. Chem. 2005, 48, 8045-8054. JC Milne et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007, 450(7170), 712-716. JM Solomon et al. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol. 2006, 26(1), 28-38. Y Zhang et al. Deacetylation of cortactin by SIRT1 promotes cell migration. Oncogene. 2009, 28(3), 445-60. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Diabetes & Metabolism Epigenetics DNA-damage Response EC 3.5.1.98 SIRT Potent and selective SIRT1 inhibitor Chemical name 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Parent CAS No. [49843-98-3] Order Size Unit Price Stock 10 mg €90.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Selisistat - EX 527Axon 1956 CAS [49843-98-3] MF C13H13ClN2O
Description
Potent and selective deacetylase sirtin 1 (SIRT1) inhibitor; a useful tool for studying the relationship between SIRT1 and cell regulation; a potential agent the treatment of Huntington’s Disease (HD)
Potent and selective SIRT1 inhibitor
Chemical name6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Parent CAS No.[49843-98-3] |
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