产品名称

SRT 1720 tetrahydrochloride

产品货号

Axon 1875 CAS [1001645-58-4] MF C25H23N7OS.4HClMW 615.41 Purity: 99% Soluble in water and DMSO Description A small-molecule activator of the sirtuin subtype SIRT1; 1000x more potent than resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function References Certificates Categories Extra info JC Milne et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007, 450(7170), 712–7160. H Dai et al. SIRT1 activation by small molecules - kinetic and biophysical evidence for direct interaction of enzyme and activator. J. Biol. Chem. 2010, 285(43), 32695–32703. E Callaway. GlaxoSmithKline strikes back over anti-ageing pills: Drugs do work as thought, says pharmaceutical giant. Nature 2010-08-16. RK Minor et al. SRT1720 improves survival and healthspan of obese mice. Scientific Reports 2011, 1, 70. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Diabetes & Metabolism Epigenetics Endocrinology DNA-damage Response EC 3.5.1.98 SIRT Activator of the sirtuin subtype SIRT1 Chemical name N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide tetrahydrochloride Parent CAS No. [925434-55-5] Order Size Unit Price Stock 5 mg €135.00 In Stock

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现货询价，电话：010-67529703

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产品品牌

axonmedchem

产品概述

产品详情

SRT 1720 tetrahydrochloride

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1875

CAS [1001645-58-4]

MF C25H23N7OS.4HCl
MW 615.41

Purity: 99%
Soluble in water and DMSO

SRT 1720 tetrahydrochloride

Description

A small-molecule activator of the sirtuin subtype SIRT1; 1000x more potent than resveratrol. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function