产品名称

P 22077

产品货号

Axon 1906 CAS [1247819-59-5] MF C12H7F2NO3S2MW 315.32 Purity: 99% Soluble in DMSO Description Small molecule inhibitor of deubiquitinase (DUB), specific on ubiquitin-specific protease 7 (USP7) and the closely related USP47; Inhibits USP7-mediated p53 deubiquitination References Certificates Categories Extra info M Altun et al. Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes. Chem. Biol. 2011, 18, 1401–1412. X Tian et al. Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format. Assay Drug Dev. Technol. 2011, 9(2), 165-173. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Ubiquitin EC 3.4.19.12 Deubiquitinase Inhibitor of deubiquitinase USP7 and USP47 Chemical name 1-(5-(2,4-difluorophenylthio)-4-nitrothiophen-2-yl)ethanone Parent CAS No. [1247819-59-5] Order Size Unit Price Stock 10 mg €95.00 In Stock

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现货询价，电话：010-67529703

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产品品牌

axonmedchem

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P 22077

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1906

CAS [1247819-59-5]

MF C12H7F2NO3S2
MW 315.32

Purity: 99%
Soluble in DMSO

P 22077

Description

Small molecule inhibitor of deubiquitinase (DUB), specific on ubiquitin-specific protease 7 (USP7) and the closely related USP47; Inhibits USP7-mediated p53 deubiquitination

M Altun et al. Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes. Chem. Biol. 2011, 18, 1401–1412.

X Tian et al. Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format. Assay Drug Dev. Technol. 2011, 9(2), 165-173.

Inhibitor of deubiquitinase USP7 and USP47

Chemical name

1-(5-(2,4-difluorophenylthio)-4-nitrothiophen-2-yl)ethanone

Parent CAS No.

[1247819-59-5]

产品资料