产品名称 | Eeyarestatin I - ES1 | ERAD inhibitor 1 | p97 inhibitor 1 |
产品货号 | Axon 1798 CAS [412960-54-4] MF C27H25Cl2N7O7MW 630.44 Purity: 98% Soluble in DMSO Description Potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination References Certificates Categories Extra info BC Cross et al. Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. J. Cell Sci. 2009, 122(Pt 23), 4393-4400. MO Aletrari et al. Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PLoS One. 2011, 6(7), e22713. Q Wang et al. Inhibition of p97-dependent Protein Degradation by Eeyarestatin I. J. Biol. Chem. 2008, 283, 7445-7454. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Ubiquitin EC 3.4.19.12 Deubiquitinase Inhibitor of endoplasmic reticulum associated protein degradation (ERAD) Chemical name 3-(4-chlorophenyl)-1-(3-(4-chlorophenyl)-5,5-dimethyl-1-(2-((E)-2-((E)-3-(5-nitrofuran-2-yl)allylidene)hydrazinyl)-2-oxoethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea Parent CAS No. [412960-54-4] Order Size Unit Price Stock 2 mg €80.00 In Stock |
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产品品牌 | axonmedchem |
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Eeyarestatin I - ES1 | ERAD inhibitor 1 | p97 inhibitor 1Axon 1798 CAS [412960-54-4] MF C27H25Cl2N7O7
Description
Potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination
Inhibitor of endoplasmic reticulum associated protein degradation (ERAD)
Chemical name3-(4-chlorophenyl)-1-(3-(4-chlorophenyl)-5,5-dimethyl-1-(2-((E)-2-((E)-3-(5-nitrofuran-2-yl)allylidene)hydrazinyl)-2-oxoethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea Parent CAS No.[412960-54-4] |
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