| 产品名称 | WP 1130 - Degrasyn |
| 产品货号 | Axon 1779 CAS [856243-80-6] MF C19H18BrN3OMW 384.27 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Small molecule inhibitor of deubiquitinase (DUB) References Certificates Categories Extra info V Kapuria et al. A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination. Cell Signal. 2011, 23(12), 2076-2085. V Kapuria et al. Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. Cancer Res. 2010, 70(22), 9265-9276. LV Pham et al. Degrasyn Potentiates the Antitumor Effects of Bortezomib in Mantle Cell Lymphoma Cells In vitro and In vivo: Therapeutic Implications. Mol Cancer Ther July 2010 9; 2026. GA Bartholomeusz et al. Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells. Blood. 2007, 109(8), 3470-3478. GA Bartholomeusz et al. Degrasyn activates proteasomal-dependent degradation of c-Myc. Cancer Res. 2007, 67(8), 3912-3918. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Ubiquitin EC 3.4.19.12 Deubiquitinase Deubiquitinase Inhibitor Chemical name (S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide Parent CAS No. [856243-80-6] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
WP 1130 - DegrasynAxon 1779 CAS [856243-80-6] MF C19H18BrN3O
Description
Small molecule inhibitor of deubiquitinase (DUB)
Deubiquitinase Inhibitor
Chemical name(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide Parent CAS No.[856243-80-6] |
| 产品资料 |
