产品名称

MLN 0905

产品货号

Axon 1910 CAS [1228960-69-7] MF C24H25F3N6SMW 486.56 Purity: 98% Soluble in 0.1N HCl(aq) and DMSO Description Potent, orally available and selective polo-like kinase (PLK) 1 inhibitor References Certificates Categories Extra info MO Duffey et al. Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J. Med. Chem. 2012, 55 (1), 197-208. JQ Shi et al. MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. Mol. Cancer Ther. 2012, 11(9), 2045-2053. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology EC 2.7.11.21 PLK PLK1 inhibitor Chemical name 2-(5-(3-(dimethylamino)propyl)-2-methylpyridin-3-ylamino)-9-(trifluoromethyl)-5H-benzo[b]pyrimido[4,5-d]azepine-6(7H)-thione Parent CAS No. [1228960-69-7] Order Size Unit Price Stock 2 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

MLN 0905

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1910

CAS [1228960-69-7]

MF C24H25F3N6S
MW 486.56

Purity: 98%
Soluble in 0.1N HCl(aq) and DMSO

MLN 0905

Description

Potent, orally available and selective polo-like kinase (PLK) 1 inhibitor

MO Duffey et al. Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J. Med. Chem. 2012, 55 (1), 197-208.

JQ Shi et al. MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. Mol. Cancer Ther. 2012, 11(9), 2045-2053.

PLK1 inhibitor

Chemical name

2-(5-(3-(dimethylamino)propyl)-2-methylpyridin-3-ylamino)-9-(trifluoromethyl)-5H-benzo[b]pyrimido[4,5-d]azepine-6(7H)-thione

Parent CAS No.

[1228960-69-7]

产品资料