| 产品名称 | GSK 461364 analogue I |
| 产品货号 | Axon 1625 CAS [929095-23-8] MF C26H27ClN4O3SMW 511.04 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent and selective Polo-like kinase (PLK) 1 inhibitor, more selective at PLK1 (IC50: 2 nM) over PLK3 (IC50: 630 nM) References Certificates Categories Extra info TR Rheault et al. Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophene carboxamides: potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like properties. Bioorg. Med. Chem. Lett. 2010, 20(15), 4587-92. KA Emmitte et al. Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding. Bioorg. Med. Chem. Lett. 2009, 19(6), 1694-7. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology EC 2.7.11.21 PLK PLK1 Inhibitor Chemical name (R)-3-(1-(2-chlorophenyl)ethoxy)-5-(6-(1-methylpiperidin-4-yloxy)-1H-benzo[d]imidazol-1-yl)thiophene-2-carboxamide Parent CAS No. [929095-23-8] Order Size Unit Price Stock 5 mg €110.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
GSK 461364 analogue IAxon 1625 CAS [929095-23-8] MF C26H27ClN4O3S
Description
Potent and selective Polo-like kinase (PLK) 1 inhibitor, more selective at PLK1 (IC50: 2 nM) over PLK3 (IC50: 630 nM)
PLK1 Inhibitor
Chemical name(R)-3-(1-(2-chlorophenyl)ethoxy)-5-(6-(1-methylpiperidin-4-yloxy)-1H-benzo[d]imidazol-1-yl)thiophene-2-carboxamide Parent CAS No.[929095-23-8] |
| 产品资料 |
