产品名称

Digoxin - Digitalis

产品货号

Axon 1649 CAS [20830-75-5] MF C41H64O14MW 780.94 Purity: 98% Soluble in DMSO Description Digoxin is a successful medication in the treatment of irregular heart rhythms, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication. Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice References Certificates Categories Extra info H Zhang et al. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth. Proc Natl Acad Sci USA 2008, 105, 19579-19586. Certificate of Analysis Material Safety Data Sheet Cardiovascular Cell Signaling & Oncology ATPase (Na+K+) EC 3.6.3.9 Na+/K+ ATPase pump inhibitor Chemical name 4-((3S,5R,8R,9S,10S,12R,13S,14S,17S)-3-((2R,4S,5S,6R)-5-((2S,4S,5S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13- Parent CAS No. [20830-75-5] Order Size Unit Price Stock 10 mg €75.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Digoxin - Digitalis

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1649

CAS [20830-75-5]

MF C41H64O14
MW 780.94

Purity: 98%
Soluble in DMSO

Digoxin

Description

Digoxin is a successful medication in the treatment of irregular heart rhythms, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication.
Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice

H Zhang et al. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth. Proc Natl Acad Sci USA 2008, 105, 19579-19586.

Na+/K+ ATPase pump inhibitor

Chemical name

4-((3S,5R,8R,9S,10S,12R,13S,14S,17S)-3-((2R,4S,5S,6R)-5-((2S,4S,5S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13-

Parent CAS No.

[20830-75-5]

产品资料