产品名称 | LRE1 - RU-0204277 |
产品货号 | Axon 2664 CAS [1252362-53-0] MF C12H13ClN4SMW 280.78 Purity: 98% Soluble in DMSO Description LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM). Inhibition occurs by occupying the binding site of the physiological activator HCO3-, preventing sAC-dependent processes in cellular and physiological systems. LRE1 also inhibited cAMP accumulation in 4-4 cells (IC50 value 11 μM). Overall, this sAC inhibitor combines high potency and selectivity with stability, solubility and lack of cytotoxicity. KEYWORDS: LRE1 | Allosteric sAC inhibitor | supplier | RU-0204277 | LRE 1 | LRE-1 | RU 0204277 | RU0204277 | CAS [1252362-53-0] | ATP | Adenylate cyclase | Inhibitor | Enzymes |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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LRE1 - RU-0204277Axon 2664 CAS [1252362-53-0] MF C12H13ClN4S
DescriptionLRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM). Inhibition occurs by occupying the binding site of the physiological activator HCO3-, preventing sAC-dependent processes in cellular and physiological systems. LRE1 also inhibited cAMP accumulation in 4-4 cells (IC50 value 11 μM). Overall, this sAC inhibitor combines high potency and selectivity with stability, solubility and lack of cytotoxicity. KEYWORDS: LRE1 | Allosteric sAC inhibitor | supplier | RU-0204277 | LRE 1 | LRE-1 | RU 0204277 | RU0204277 | CAS [1252362-53-0] | ATP | Adenylate cyclase | Inhibitor | Enzymes
Allosteric soluble adenylyl cyclase (sAC) inhibitor
Chemical name6-Chloro-N4-cyclopropyl-N4-(thiophen-2-ylmethyl)pyrimidine-2,4-diamine Parent CAS No.[1252362-53-0] |
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