产品名称 LRE1 - RU-0204277
产品货号 Axon 2664 CAS [1252362-53-0] MF C12H13ClN4SMW 280.78 Purity: 98% Soluble in DMSO Description LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM). Inhibition occurs by occupying the binding site of the physiological activator HCO3-, preventing sAC-dependent processes in cellular and physiological systems. LRE1 also inhibited cAMP accumulation in 4-4 cells (IC50 value 11 μM). Overall, this sAC inhibitor combines high potency and selectivity with stability, solubility and lack of cytotoxicity. KEYWORDS: LRE1 | Allosteric sAC inhibitor | supplier | RU-0204277 | LRE 1 | LRE-1 | RU 0204277  | RU0204277  | CAS [1252362-53-0] | ATP | Adenylate cyclase | Inhibitor | Enzymes
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

LRE1 - RU-0204277

Based on 13 reference(s) in Google Scholar 8 10 13

Axon 2664

CAS [1252362-53-0]

MF C12H13ClN4S
MW 280.78

  • Purity: 98%
  • Soluble in DMSO

LRE1

Description

LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM). Inhibition occurs by occupying the binding site of the physiological activator HCO3-, preventing sAC-dependent processes in cellular and physiological systems. LRE1 also inhibited cAMP accumulation in 4-4 cells (IC50 value 11 μM). Overall, this sAC inhibitor combines high potency and selectivity with stability, solubility and lack of cytotoxicity.

KEYWORDS: LRE1 | Allosteric sAC inhibitor | supplier | RU-0204277 | LRE 1 | LRE-1 | RU 0204277  | RU0204277  | CAS [1252362-53-0] | ATP | Adenylate cyclase | Inhibitor | Enzymes

产品资料