产品名称

Digoxigenin bisdigitoxoside

产品货号

Axon 1695 CAS [5297-05-2] MF C35H54O11MW 650.80 Purity: 98% Soluble in DMSO Description A metabolite of Digoxin (Axon 1649). Digoxin is a heart medication. Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice. KEYWORDS: Digoxigenin bis-digitoxiside | supplier | HIF-1 inhibitor | Digoxigenin bisdigitoxiside | CAS [5297-05-2] | ATP | ATPase (Na+K+) | Inhibitor | Enzymes

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axonmedchem

产品概述

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Digoxigenin bisdigitoxoside

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1695

CAS [5297-05-2]

MF C35H54O11
MW 650.80

Purity: 98%
Soluble in DMSO

Digoxigenin bisdigitoxoside

Description

A metabolite of Digoxin (Axon 1649). Digoxin is a heart medication. Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition.
Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice.

U. Abshagen and N. Rietbrock. Metabolism of Digoxigenin, digoxigeninmonodigitoxoside and digoxigeninbisdigitoxoside in rats. NAUNYN-SCHMIEDEBERG's ARCH. PHARMACOL. 1973, 276(2), 157-166.

Metabolite of Digoxin

Chemical name

4-((3S,5R,10S,12R,13S,14S,17R)-3-((2R,4S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one

Parent CAS No.

[5297-05-2]

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