产品名称

NSC 59984

产品货号

Axon 2564 CAS [803647-40-7] MF C12H15N3O4MW 265.27 Purity: 100% Soluble in 0.1N HCl(aq) and DMSO Description Activator of p53 that restores wild-type p53 signaling via p73 activation, specifically in mutant p53-expressing colorectal cancer cells, inducing cell death in colorectal cancer cells with minimal genotoxicity and without evident toxicity toward normal cells. Remarkebly, NSC 59984 induces degradation of several p53 mutants through MDM2-mediated ubiquitination. KEYWORDS: NSC 59984 | supplier | p53 activator | NSC59984 | NSC-59984 | CAS [803647-40-7] | DNA-RNA | p53 | Activator | Transcription Factor | MDM2 | p73 | HDM | colorectal | cancer | ubiquitination | apoptosis

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

NSC 59984

Based on 15 reference(s) in Google Scholar 9 10 15

Axon 2564

CAS [803647-40-7]

MF C12H15N3O4
MW 265.27

Purity: 100%
Soluble in 0.1N HCl(aq) and DMSO

NSC 59984

Description

Activator of p53 that restores wild-type p53 signaling via p73 activation, specifically in mutant p53-expressing colorectal cancer cells, inducing cell death in colorectal cancer cells with minimal genotoxicity and without evident toxicity toward normal cells. Remarkebly, NSC 59984 induces degradation of several p53 mutants through MDM2-mediated ubiquitination.

KEYWORDS: NSC 59984 | supplier | p53 activator | NSC59984 | NSC-59984 | CAS [803647-40-7] | DNA-RNA | p53 | Activator | Transcription Factor | MDM2 | p73 | HDM | colorectal | cancer | ubiquitination | apoptosis