产品名称

CM1

产品货号

Axon 2479 CAS [1643659-63-5] MF C14H22N2O3MW 266.34 Purity: 100% Soluble in water and DMSO Description Orally active iron chelator with high afﬁnity and selectivity for iron(III) (relative metal complex stability constants of pFe(III)= 20.3; pCu(II)= 9.8; pZn(II)= 6.2) and a suit-able partition coefﬁcient to permeate membranes. CM1 is able to penetrate hepatocytes and relatively non toxic. Potential therapeutic for patients suffering from thalassaemia related iron overload Moreover, CM1 shows an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 µM). KEYWORDS: CM1 | supplier | Iron chelator | CAS [1643659-63-5] | Iron (III) | FE(III) | Chelator | thalassaemia | hepatocytes | malaria | parasite | Plasmodium

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

CM1

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2479

CAS [1643659-63-5]

MF C14H22N2O3
MW 266.34

Purity: 100%
Soluble in water and DMSO

CM1

Description

Orally active iron chelator with high afﬁnity and selectivity for iron(III) (relative metal complex stability constants of pFe(III)= 20.3; pCu(II)= 9.8; pZn(II)= 6.2) and a suit-able partition coefﬁcient to permeate membranes. CM1 is able to penetrate hepatocytes and relatively non toxic. Potential therapeutic for patients suffering from thalassaemia related iron overload Moreover, CM1 shows an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 µM).