产品名称

SMER 28

产品货号

Axon 2627 CAS [307538-42-7] MF C11H10BrN3MW 264.12 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Small molecule enhancer of rapamycin that enhances the clearance of mutant aggregate-prone proteins by autophagy in mammalian cell models of Huntington’s and Parkinson’s disease, independent of mTOR and Atg5 pathways. SMER28 also promotes reprogramming of fibroblasts (the conversion efficiency for adult tail-tip fibroblasts in particular) into neural stem cells, if combined with RG108 (Axon 1691) and Parnate. KEYWORDS: SMER 28 | supplier | Autophagy inducer; SMER | SMER28 | SMER-28 | CAS [307538-42-7] | Small molecule enhancer of rapamycin | SMER | clearance | Huntington’s | Parkinson’s | reprogramming | fibroblasts | neural stem cells

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

SMER 28

Based on 7 publications in PubMed 9 10 7

Axon 2627

CAS [307538-42-7]

MF C11H10BrN3
MW 264.12

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

SMER 28

Description

Small molecule enhancer of rapamycin that enhances the clearance of mutant aggregate-prone proteins by autophagy in mammalian cell models of Huntington’s and Parkinson’s disease, independent of mTOR and Atg5 pathways. SMER28 also promotes reprogramming of fibroblasts (the conversion efficiency for adult tail-tip fibroblasts in particular) into neural stem cells, if combined with RG108 (Axon 1691) and Parnate.