产品名称

NVP-BKM120 - BKM 120

产品货号

Axon 1797 CAS [944396-07-0] MF C18H21F3N6O2MW 410.39 Purity: 98% Soluble in DMSO Description Potent, selective, orally bioavailable class I PI3K inhibitor References Certificates Categories Extra info CW Lindsley et al. (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: discovery of a new tool compound with activity in the OSS mouse model of addiction. ACS Chem. Neurosci. 2011, 2(8), 471-482. D Koul et al. Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells. Clin Cancer Res. 2012, 18(1), 184-195. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153 Class I PI3K inhibitor Chemical name 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine Parent CAS No. [944396-07-0] Order Size Unit Price Stock 5 mg €90.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

NVP-BKM120 - BKM 120

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1797

CAS [944396-07-0]

MF C18H21F3N6O2
MW 410.39

Purity: 98%
Soluble in DMSO

NVP-BKM120

Description

Potent, selective, orally bioavailable class I PI3K inhibitor

CW Lindsley et al. (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: discovery of a new tool compound with activity in the OSS mouse model of addiction. ACS Chem. Neurosci. 2011, 2(8), 471-482.

D Koul et al. Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells. Clin Cancer Res. 2012, 18(1), 184-195.

Class I PI3K inhibitor

Chemical name

5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine

Parent CAS No.

[944396-07-0]

产品资料