产品名称 KU 55933
产品货号 Axon 1367 CAS [587871-26-9] MF C21H17NO3S2MW 395.49 Purity: 99% Soluble in DMSO Description Potent, ATP-competitive and selective ATM inhibitor (Ki = 2.2 nM, IC50 = 13 nM) References Certificates Categories Extra info I Hickson et al. Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM. Cancer Res. 2004, 64, 9152.   A Lau et al. Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase. Nat. Cell Biol. 2005, 7, 493-500.   Y Li and DQ Yang. The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt. Mol. Cancer Ther. 2010, 9, 113. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology ATM p53-Tumor Suppression PI3K-Akt-mTOR DNA-damage Response EC 2.7.11.1 ATM inhibitor Chemical name 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one Parent CAS No. [587871-26-9] Order Size Unit Price Stock 10 mg €125.00 In Stock
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