产品名称 | BAG 956 - NVP-BAG956 |
产品货号 | Axon 1282 CAS [853910-02-8] MF C28H21N5MW 427.50 Purity: 99% Soluble in DMSO Description Potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor in vitro and in vivo, with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 α, β, δ and γ and PDPK1 kinases, respectively References Certificates Categories Extra info R Marone et al. Targeting Melanoma with Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors. Mol. Cancer Res. 2009, 7(4), 601-613. SM Maria, P Furet and F Stauffer. Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway. Future Med. Chem. 2009, 1(1), 137-155. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153 PDPK PI3K and PDPK1 inhibitor Chemical name 2-methyl-2-[4-(2-methyl-8-pyridin-3-ylethynyl-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile Parent CAS No. [853910-02-8] Order Size Unit Price Stock 5 mg €95.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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BAG 956 - NVP-BAG956Axon 1282 CAS [853910-02-8] MF C28H21N5
Description
Potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor in vitro and in vivo, with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 α, β, δ and γ and PDPK1 kinases, respectively
PI3K and PDPK1 inhibitor
Chemical name2-methyl-2-[4-(2-methyl-8-pyridin-3-ylethynyl-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile Parent CAS No.[853910-02-8] |
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