产品名称

GMC 1-161

产品货号

Axon 2851 CAS [95316-97-5] MF C19H22N4OMW 322.40 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Analogue of clozapine (Axon 1146); devoid of affinity for the DA D1 receptor, but with affinities at 5-HT2A/2C, hM1 and DA D2 receptors. KEYWORDS: GMC 1-161 | supplier | Clozapine analogue | GMC1-161 | GMC1161 | CAS [95316-97-5] | Serotonin | 5-HT2A | 5-HT2C | CHRM1 | D2 | Agonist | Receptors

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

GMC 1-161

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2851

CAS [95316-97-5]

MF C19H22N4O
MW 322.40

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

GMC 1-161

Description

Analogue of clozapine (Axon 1146); devoid of affinity for the DA D1 receptor, but with affinities at 5-HT2A/2C, hM1 and DA D2 receptors.

KEYWORDS: GMC 1-161 | supplier | Clozapine analogue | GMC1-161 | GMC1161 | CAS [95316-97-5] | Serotonin | 5-HT2A | 5-HT2C | CHRM1 | D2 | Agonist | Receptors

Y Liao et al. Synthesis and pharmacological evaluation of triflate-substituted analogues of clozapine: identification of a novel atypical neuroleptic. J Med Chem. 1997 Dec 5;40(25):4146-53.

Y Liao et al. New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation. J Med Chem. 1999 Jun 17;42(12):2235-44.

CNS D2 5-HT2A 5-HT2C CHRM1 A17

Clozapine analog with 5-HT2A, M1 and D2 affinity, devoid of D1 affinities

Chemical name

2-Methoxy-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Parent CAS No.

[95316-97-5]

产品资料